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KMID : 0375319920140020313
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Journal of Clinical Pathology and Quality Control
1992 Volume.14 No. 2 p.313 ~ p.317
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A Study on the Serological Diagnosis of EBV Infection by Combination of three antibodies to EBV-IgM, EA-IgG, and NA-IgG
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Lee Chang-Hoon
Chun Hea-Sun
Kim Hyun-Sook
Song Kyoung-Soon
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Abstract
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We evaluated the combination test of three antibodies to EBV recombinant antigens(EBV -IgM, EA-IgG, NA-IgG).
Of 29 normal adults and 14 normal children, patterns representing previous infection[EBV -IgM (- ), EA-IgG (+ or, - ), NA-IgG (+) ] were observed in 24(83%), and 5(36%), respectively. Patterns representing acute reactivation(+/-/+) were observed in 5(12%) of 43 normal groups.
Of 14 patients, clinically suspecting EBV infection, EBV-IgM were positive in 7(50%). Of these 7 patients, 4 were diagnosed as suffering acute reactivation (+/-/+) and 3 were diagnosed as having typical or early stage of primary infection (+/+ or, -/-).
In conclusion, these findings indicate that the serological patterns using 3 antibody panel tests above mentioned, would be more useful to evaluate the EBV infection than using only one antibody test.
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KEYWORD
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EBV infection, EBV-IgM, EA-IgG, NA-IgG
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